Striking Hotel Exterior1 Beautifully Decorated Hotel Lobby2 One 1King Bed Non-Smoking3 King Bed Accessible Non-Smoking4 Two Queen Beds Non-Smoking5

Welcome to

Knights Inn New Florence

Welcome to Knights Inn New Florence, your comfortable and affordable hotel in Florence, Missouri. Conveniently located off I-70, we offer the perfect place to rest and recharge while exploring the local area. Whether you're visiting nearby wineries, enjoying outdoor adventures, or just passing through, our Florence, Missouri hotel is here to provide all the essentials for a pleasant stay.
At Knights Inn New Florence, we believe in keeping things simple. Our clean, cozy rooms are designed with your comfort in mind, offering all the basics, including free Wi-Fi, cable TV, and a comfortable bed.

Start your day right with our complimentary breakfast and stay connected throughout your visit with our free high-speed internet.
Traveling with pets? We understand how important it is to have your furry friends with you. That's why we welcome pets at our hotel, though some restrictions and charges may apply.
Whether you're here for a short stay or an extended visit, Knights Inn New Florence offers a great location near top local attractions, making it easy to explore everything Florence, Missouri has to offer.

Business Travel:
If you're traveling for work and need a convenient and comfortable place to stay, our hotel in Florence, MO is the perfect choice. Located near major highways, we're just minutes away from key business centers and local attractions. For those visiting local sites like the New Florence United Methodist Church, our hotel offers easy access and a peaceful environment for rest after a busy day. With free Wi-Fi and other amenities, business travelers will find everything they need for a productive stay at one of the top hotels in Florence, Missouri.

Family Travel:
Looking for a relaxing and fun getaway with your family? Knights Inn New Florence is a great option for those in search of Florence, Missouri motels that offer comfort and convenience. Enjoy nearby attractions like parks and wineries, and explore the town’s historic sites, such as the New Florence United Methodist Church. As a budget hotel in Florence, MO, we provide family-friendly amenities like free breakfast and spacious rooms to make your stay both enjoyable and affordable.

Affordable Stay:
For travelers seeking an affordable hotel in Florence, Missouri, Knights Inn New Florence is the ideal choice. Whether you’re passing through or staying a few days to explore the local area, we offer clean, comfortable rooms at unbeatable prices. Conveniently located near St. Louis Lambert Intl. Airport hotels, we provide easy access to major attractions without breaking the bank.

Safe And Peaceful Stay:
At Knights Inn New Florence, we prioritize your safety and comfort. Our hotel in Florence, MO offers a peaceful atmosphere, perfect for a restful night after a long day of travel. As one of the most trusted Florence, MO pet-friendly hotels, we ensure that both you and your furry companions feel safe and welcome. Relax and enjoy a quiet stay at one of the best hotels in Florence, Missouri.

Stone Hill Winery


Savor award-winning wines at one of Missouri’s oldest wineries.

Knights Inn New Florence Rooms

Unlock Your Stay – Easy Booking, Unforgettable Experience.

2 Queen Beds Accessible Non-Smoking

Sleeps 4
/
2 Queen beds

Book Now

1 King Bed Accessible Non-Smoking

Sleeps 2
/
1 King bed

Book Now

1 King Bed Non-Smoking

Sleeps 2
/
1 King bed

Book Now

2 Queen Beds Non-Smoking

Sleeps 4
/
2 Queen beds

Book Now

Fuel Your Day with a Free Breakfast and All-Day Coffee!


Start Your Day with a Complimentary Breakfast We’ve got your mornings taken care of! Wake up to a delicious complimentary breakfast, perfect for getting your day started right. Plus, enjoy free coffee and tea in our lobby, available all day long. Looking to explore local dining spots? Stop by the front desk for personalized recommendations—we’re here to help you discover the best nearby options.

Explore the Best of New Florence, Missouri

Conveniently located off I-70, our hotel offers easy access to the charming and historic town of Hermann, Missouri. Stay with us and take some time to explore the unique attractions and natural beauty the area has to offer.

Stone Hill Winery – Savor award-winning wines at one of Missouri’s oldest wineries.

Graham Cave State Park – Discover ancient history and scenic trails at this fascinating park.

Eco Adventures Zip Line – Experience the thrill of zip-lining through breathtaking landscapes.

Curling Vine Winery – Enjoy a relaxing day of wine tasting and vineyard views.

Hermann Wine Trail – Follow the trail and sample exceptional wines from renowned local wineries.

Find fun things to do near Anderson